Figure 2: Polygonum multiflorum and Codonopsis pilosula Granule effectively regulates the proportion of labile collagen fibers in the plaques at the aortic roots of ApoE^−/− and p66shc^−/+ mice. MASSON staining revealed that the proportion of labile collagen fibers in the aortic root plaques was significantly reduced in the Polygonum multiflorum and Codonopsis pilosula Granule group. **P < 0.01 versus the WT group, *P < 0.05 versus the WT group,^##P < 0.01 versus the Saline group,^#P < 0.05 versus the WT group; t-test