| ORIGINAL ARTICLE |
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| Year : 2018 | Volume
: 1
| Issue : 2 | Page : 50-55 |
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Aortic pulse wave velocity and augmentation [email protected] measured by oscillometric pulse wave analysis in Gujarati nonhypertensives
Jayesh Dalpatbhai Solanki, Hemant B Mehta, Chinmay J Shah
Department of Physiology, Government Medical College, Bhavnagar, Gujarat, India
Correspondence Address:
Jayesh Dalpatbhai Solanki
F1, Shivganga Appartments, Plot No 164, Bhayani Ni Waadi, Opp. Bawaliya Hanuman Temple, Gadhechi Wadlaa Road, Bhavnagar - 364 001, Gujarat
India
 Source of Support: None, Conflict of Interest: None  | 2 |
DOI: 10.4103/VIT.VIT_10_18
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BACKGROUND: Augmentation indexes (AIxs) and pulse wave velocity (PWV) are arterial stiffness parameters. They can be studied by pulse wave analysis (PWA) noninvasively. Before use, AIx and PWV need normative baseline study to find the predictors.
MATERIALS AND METHODS: We conducted a cross-sectional study in 801 nonhypertensives, aged 15–65 (divided into five subgroups) years. PWA was accomplished by Mobil-o-Graph (IEM, Germany) based on oscillometric principle and cardiovascular parameters reported were further analyzed. Value of P < 0.05 was taken as statistical significance.
RESULTS: There were five age-based subgroups from 15 to 65 years, showing an increase in [email protected] and PWV with age. Females had significantly higher AIx in male in age groups (31.4 vs. 25.8, 34.95 vs. 27.21, 32.62 vs. 27.61, 34.32 vs. 26.36, 37.09 vs. 29.63; P < 0.05 for all), but PWV was higher in males than females in young age group (15–24 years-4.94 vs. 4.71, 25–34 years-5.28 vs. 5.12, 35–44 years-6.00 vs. 5.84; P < 0.05 in all) and in females than males in older age group (45–54 years-6.88 vs. 6.78,55–65 years-8.13 vs. 8.03). Major positive significant predictors of PWV were age, Body Mass Index, and systolic blood pressure; and of [email protected] were age, height (negative), heart rate, and pulse pressure. [email protected] and PWV showed a positive correlation with each other across all age group in either sex except for 55–65 years and 25–34 years age groups.
CONCLUSIONS: Oscillometric measurement of PWV and [email protected] is feasible in our population. They are dependent on each other and age, totally not dependent on blood pressure and have difference in predictors. This baseline data can be used as a reference for future studies. |
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