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  Indian J Med Microbiol
 

Figure 3: Polygonum multiflorum and Codonopsis pilosula Granule effectively reduces the percent of the aortic area containing lipid deposits and blood lipid levels in ApoE−/− and p66shc−/+ mice. (a) Gross staining with oil red O showed that the percent area of lipid deposition in the aorta was markedly reduced in the Polygonum multiflorum and Codonopsis pilosula Granule group. **P < 0.01 versus WT group, *P < 0.05 versus WT group,##P < 0.01 versus Saline group,#P < 0.05 versus WT group; t-test. (b) Polygonum multiflorum and Codonopsis pilosula Granule significantly improves blood lipid profile in ApoE−/− and p66shc−/+ mice. Serum TG, TC and LDL-C levels were markedly reduced while serum HDL-C level was significantly elevated in the Polygonum multiflorum and Codonopsis pilosula Granule group. **P < 0.01 versus the WT group, *P < 0.05 versus the WT group,##P < 0.01 versus the Saline group,#P < 0.05 versus the WT group; t-test

Figure 3: <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule effectively reduces the percent of the aortic area containing lipid deposits and blood lipid levels in ApoE<sup>−/−</sup> and p66shc<sup>−/+</sup> mice. (a) Gross staining with oil red O showed that the percent area of lipid deposition in the aorta was markedly reduced in the <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule group. **<i>P</i> < 0.01 versus WT group, *<i>P</i> < 0.05 versus WT group,<sup>##</sup><i>P</i> < 0.01 versus Saline group,<sup>#</sup><i>P</i> < 0.05 versus WT group; <i>t</i>-test. (b) <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule significantly improves blood lipid profile in ApoE<sup>−/−</sup> and p66shc<sup>−/+</sup> mice. Serum TG, TC and LDL-C levels were markedly reduced while serum HDL-C level was significantly elevated in the <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule group. **<i>P</i> < 0.01 versus the WT group, *<i>P</i> < 0.05 versus the WT group,<sup>##</sup><i>P</i> < 0.01 versus the Saline group,<sup>#</sup><i>P</i> < 0.05 versus the WT group; <i>t</i>-test