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  Indian J Med Microbiol
 

Figure 1: Polygonum multiflorum and Codonopsis pilosula Granule effectively ameliorates aortic root lesions in ApoE−/− and p66shc−/+ mice. The results of H and E staining showed that the area of AS plaques had significantly shrunk, and the number of plaques on the verge of rupture was markedly reduced in the Polygonum multiflorum and Codonopsis pilosula Granule group. The lesions developed in the Polygonum multiflorum and Codonopsis pilosula Granule group were mainly in the fibrous plaque stage. **P < 0.01 versus the WT group, *P < 0.05 versus the WT group,##P < 0.01 versus the saline group,#P < 0.05 versus the WT group; t-test

Figure 1: <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule effectively ameliorates aortic root lesions in ApoE<sup>−/−</sup> and p66shc<sup>−/+</sup> mice. The results of H and E staining showed that the area of AS plaques had significantly shrunk, and the number of plaques on the verge of rupture was markedly reduced in the <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule group. The lesions developed in the <i>Polygonum multiflorum</i> and <i>Codonopsis pilosula</i> Granule group were mainly in the fibrous plaque stage. **<i>P</i> < 0.01 versus the WT group, *<i>P</i> < 0.05 versus the WT group,<sup>##</sup><i>P</i> < 0.01 versus the saline group,<sup>#</sup><i>P</i> < 0.05 versus the WT group; <i>t</i>-test