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REVIEW ARTICLE
Year : 2020  |  Volume : 3  |  Issue : 2  |  Page : 54-57

Coronavirus disease-2019 and its macro- and microvascular implications: The Italian Microcirculation Society's analyses


1 Department of Microcirculation, J.F. Merlen Research Centre for Vascular Disease, Frosinone, Italy
2 Department of Clinical Microcirculation, Società Italiana di Microcircolazione, Rome, Italy
3 Department of Vascular Surgery, Presidio Ospedaliero di Tortona ASL Alessandria, Tortona, Italy
4 Department of Angiology, Azienda Ospedaliera Universitaria Policlinico Vittorio Emanuele Unità Operativa Angiologia Ospedale San Marco, Catania, Sicily, Italy
5 Department of Vascular Surgery, Aurelia Hospital, Rome, Italy
6 Department of Angiology, Azienda Ospedaliera dei Colli, Naples, Italy
7 Department of Angiology, Casa di Cura Privata Accreditata I.N.I. – Div. Città Bianca Veroli, La Vittoria, Rome, Italy
8 Department of Angiology, Azienda Ospedaliera San Camillo Forlanini, Rome, Italy
9 Department of Dermatology, Università di Trieste, Trieste, Italy

Correspondence Address:
Dr. Salvino Bilancini
Via Mola Vecchia, 4, 03100 Frosinone
Italy
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/VIT.VIT_12_20

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Coronavirus disease-2019 (COVID-19) is characterized by a violent multiorgan inflammation which activates coagulation, thereby inducing arterial and venous thrombosis. In particular, it leads to thrombi of the microcirculation in a variety of organs and apparatus. Compelling data have confirmed this hypothesis and studies that demonstrate how coagulation parameters, such as D-dimer and fibrinogen, might provide important prognostic evidence. On reviewing the relevant literature available to date, the authors have set out to express their opinion as to the need not to underestimate the thrombotic component of COVID-19 at all levels (arterial, venous, and microcirculatory).


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